MEGALIS

Price range: $90.00 through $315.00

Generic Name: Tadalafil
Manufacturer: Macleods Pharmaceuticals Pvt Ltd
Packaging: 4 Tablets in Strip
Delivery Time: 6 To 15 days
SKU: Megalis
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MEGALIS TABLETS – Patient Information Guide

What This Medicine Is

Megalis is a prescription medication that contains Tadalafil as its active ingredient. It belongs to a group of medicines called phosphodiesterase type 5 (PDE5) inhibitors. This medicine is primarily used to help adult men who experience difficulty in achieving or maintaining adequate blood flow to certain areas of the body during physical intimacy.

Megalis tablets are available in various strengths and are manufactured under strict quality standards. This medication requires a valid prescription from a licensed healthcare provider and should only be used under medical supervision.

How This Medicine Works

Megalis works by helping to relax the smooth muscles in blood vessel walls, which allows improved blood circulation to specific areas of the body when natural stimulation occurs.

Here’s a simple explanation: When certain natural signals are sent in your body, a chemical called cGMP is released. This chemical helps blood vessels widen. However, another enzyme called PDE5 breaks down cGMP too quickly in some people. Megalis temporarily blocks PDE5, allowing cGMP to work longer and blood vessels to remain relaxed for better circulation.

It’s important to understand that this medicine does not work automatically—it requires natural physical or psychological stimulation to be effective. The medicine simply supports your body’s natural response mechanisms.

Medical Uses

Megalis (Tadalafil) has been clinically approved for the following medical conditions in adult men:

1. Erectile Dysfunction (ED) A condition where men have persistent difficulty achieving or maintaining adequate rigidity during intimate activity. This medication helps improve the body’s natural response when appropriate stimulation occurs.

2. Benign Prostatic Hyperplasia (BPH) An age-related condition involving enlargement of the prostate gland, which can cause urinary symptoms such as difficulty starting urination, weak stream, or frequent nighttime urination.

3. Combined ED and BPH Some men experience both conditions simultaneously, and Tadalafil may be prescribed to address both concerns with a single medication.

Note: Megalis should only be used for conditions diagnosed by a qualified healthcare provider. Self-diagnosis and self-medication can be harmful to your health.

Comparison Table: Megalis vs Other Tadalafil Brands

Feature Megalis Cialis Tadacip Vidalista
Active Ingredient Tadalafil Tadalafil Tadalafil Tadalafil
Manufacturer Macleods Pharmaceuticals Eli Lilly Cipla Centurion Laboratories
Available Strengths 10mg, 20mg 2.5mg, 5mg, 10mg, 20mg 10mg, 20mg 5mg, 10mg, 20mg, 40mg, 60mg
Prescription Status Rx only Rx only Rx only Rx only
Duration of Action Up to 36 hours Up to 36 hours Up to 36 hours Up to 36 hours
Market Position Generic (affordable) Original brand Generic Generic
Typical Cost Range Budget-friendly Premium pricing Mid-range Budget-friendly

Important Note: All these medications contain the same active ingredient and work similarly. The choice between brands often depends on availability, cost, and physician recommendation. Effectiveness may vary slightly between individuals, but all authentic products meet regulatory standards.

How to Take This Medicine Safely

General Guidelines:

  • Timing: Megalis can be taken with or without food. However, heavy or high-fat meals may delay how quickly the medicine starts working.
  • Dosage: Only take the dose prescribed by your doctor. Do not take more than one tablet in a 24-hour period unless specifically instructed by your healthcare provider.
  • Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
  • When to take: The medicine can be taken 30 minutes to several hours before anticipated activity, as it remains active in the body for an extended period.
  • Alcohol: Limit alcohol consumption when using this medicine, as excessive drinking can reduce effectiveness and increase the risk of side effects.

Important Reminders:

  • Never share your medication with others, even if they have similar symptoms
  • Do not adjust your dose without consulting your doctor
  • If you miss a dose and take this medicine regularly (for BPH), take it as soon as you remember unless it’s almost time for the next dose
  • This medication does not protect against sexually transmitted infections

Expected Benefits

When used appropriately under medical supervision, Megalis may help with:

For Erectile Dysfunction:

  • Improved ability to achieve adequate firmness during intimate moments when natural stimulation is present
  • Longer window of opportunity (up to 36 hours) for spontaneous intimacy without strict timing requirements
  • Better confidence in intimate situations
  • Improved relationship satisfaction for some couples

For Benign Prostatic Hyperplasia:

  • Easier initiation of urination
  • Reduced urgency and frequency of bathroom visits
  • Better nighttime sleep due to fewer interruptions
  • Improved urine flow

Timeline: Most men notice effects within 30-60 minutes after taking the tablet, though this varies among individuals. The medicine may remain effective for up to 36 hours, which is why it’s sometimes called the “weekend pill.”

Remember: Results vary from person to person. Some men respond better than others, and it may take several attempts to achieve optimal results. Patience and open communication with your healthcare provider are important.

Possible Side Effects

Like all medications, Megalis can cause side effects, although not everyone experiences them.

Common Side Effects (may affect up to 1 in 10 people):

  • Headache
  • Facial flushing (warmth or redness in face, neck, or chest)
  • Indigestion or upset stomach
  • Back pain or muscle aches
  • Nasal congestion or runny nose
  • Dizziness

These mild effects usually go away on their own within a few hours and are generally not serious.

Less Common Side Effects:

  • Nausea
  • Vision changes (blurred vision, sensitivity to light, bluish tinge)
  • Increased tear production
  • Rapid heartbeat
  • Low blood pressure symptoms (feeling faint)

Serious Side Effects (Seek immediate medical attention):

  • Sudden vision loss in one or both eyes – This could be a sign of a serious eye problem called NAION
  • Sudden hearing loss or ringing in the ears – Stop taking the medicine immediately
  • Chest pain or irregular heartbeat during or after intimate activity – Do not attempt to drive yourself to the hospital
  • Erection lasting more than 4 hours (priapism) – This is a medical emergency requiring immediate treatment to prevent permanent damage
  • Severe allergic reactions – Difficulty breathing, swelling of face/lips/tongue, severe rash

What to do: If you experience mild side effects that are bothersome, discuss them with your doctor at your next visit. For serious side effects, seek emergency medical care immediately.

Warnings & Precautions

Do NOT take Megalis if you:

  • Are taking nitrate medications for chest pain (e.g., nitroglycerin, isosorbide) – This combination can cause a dangerous drop in blood pressure
  • Are allergic to Tadalafil or any ingredients in the tablet
  • Have been advised by your doctor to avoid intimate activity due to heart problems
  • Have had a heart attack or stroke in the past 6 months
  • Have severe liver or kidney disease
  • Have low blood pressure or uncontrolled high blood pressure
  • Have a rare inherited eye condition called retinitis pigmentosa

Use with caution and inform your doctor if you:

  • Have heart disease, irregular heart rhythm, or history of heart failure
  • Have blood circulation problems
  • Have bleeding disorders or active stomach ulcers
  • Have deformation of the penis or conditions that increase risk of prolonged erection (sickle cell anemia, multiple myeloma, leukemia)
  • Are currently taking medications for high blood pressure
  • Have kidney or liver problems
  • Are over 65 years of age
  • Are taking other medications for ED or BPH

Special Populations:

  • Not for women: This medicine is not intended for use by women
  • Not for children: Megalis is only approved for adult men (18 years and older)
  • Elderly patients: Older adults may be more sensitive to side effects and may require dose adjustments

Important Safety Information:

  • Stop using this medicine and seek immediate medical help if you experience sudden vision or hearing loss
  • Do not use recreational drugs called “poppers” (amyl nitrite) while taking this medicine
  • Be cautious when driving or operating machinery until you know how this medicine affects you

Drug Interactions

Megalis can interact with several types of medications. Always inform your healthcare provider about all medicines you’re taking, including prescription drugs, over-the-counter products, herbal supplements, and vitamins.

Serious Interactions (Do Not Combine):

  • Nitrates and nitric oxide donors: Used for chest pain – can cause severe blood pressure drop
  • Riociguat: Used for pulmonary hypertension
  • Other PDE5 inhibitors: Such as sildenafil or vardenafil

Significant Interactions (Require Medical Supervision):

  • Alpha-blockers: Used for high blood pressure or prostate problems (e.g., doxazosin, tamsulosin)
  • Blood pressure medications: May enhance blood pressure-lowering effects
  • Antifungal medications: Such as ketoconazole or itraconazole – may increase Tadalafil levels
  • Antibiotics: Certain types like erythromycin or clarithromycin
  • HIV protease inhibitors: Such as ritonavir or saquinavir
  • Seizure medications: Like carbamazepine or phenytoin

Food and Lifestyle Interactions:

  • Grapefruit juice: May increase the amount of Tadalafil in your blood
  • Alcohol: Excessive consumption can increase side effects and reduce effectiveness
  • Fatty meals: May delay how quickly the medicine works

Herbal Products: Some herbal supplements may interact with this medicine. Always mention any supplements you’re taking to your healthcare provider.

Storage & Handling Instructions

Proper storage ensures your medicine remains safe and effective:

  • Temperature: Store at room temperature between 15°C to 30°C (59°F to 86°F)
  • Location: Keep in a dry place away from moisture and direct sunlight
  • Original packaging: Store tablets in their original blister pack or container until ready to use
  • Keep away from children: Store in a secure location out of reach and sight of children
  • Bathroom storage: Avoid storing in bathrooms due to humidity and temperature fluctuations
  • Do not transfer: Keep tablets in original packaging with proper labeling

Disposal:

  • Do not flush expired or unused tablets down the toilet
  • Do not throw in household trash where children or pets could access them
  • Ask your pharmacist about medication take-back programs in your area
  • Check expiration dates regularly and dispose of expired medicines properly

Travel Tips:

  • Carry medication in original labeled container
  • Keep with carry-on luggage when flying
  • Be aware of temperature exposure during travel

Frequently Asked Questions

Q1: How quickly does Megalis start working?

Most men notice effects within 30 to 60 minutes after taking the tablet. However, for some individuals, it may take up to 2 hours. The medicine works best when taken on an empty stomach or after a light meal. Remember that natural stimulation is necessary for the medication to work—it doesn’t cause automatic physical responses.

Q2: Can I take Megalis every day?

Megalis can be taken as needed or, in some cases, as a daily medication at a lower dose when prescribed for BPH or combined ED/BPH conditions. Your doctor will determine the appropriate regimen for your situation. Never take more than one standard dose in a 24-hour period unless your doctor specifically prescribes daily low-dose therapy.

Q3: What should I do if Megalis doesn’t work for me?

Several factors can affect how well the medicine works. If you don’t notice improvement after several attempts, speak with your doctor. They may adjust your dose, check for underlying conditions, review other medications you’re taking, or suggest alternative treatments. Don’t increase the dose on your own—this can be dangerous.

Q4: Is it safe to take Megalis with blood pressure medication?

This depends on the specific blood pressure medication you’re taking. Some combinations are safe under medical supervision, while others (particularly nitrates) are extremely dangerous. Always inform your doctor about all medications you take. They can determine if Megalis is appropriate for you and may need to adjust your blood pressure medication.

Q5: Can I drink alcohol while taking Megalis?

Small amounts of alcohol (1-2 drinks) are generally considered acceptable. However, excessive alcohol consumption can reduce the effectiveness of the medicine and increase the risk of side effects such as dizziness, headache, and low blood pressure. Moderation is advised.

Q6: How long does Megalis remain effective in my system?

Megalis can remain active in your body for up to 36 hours, which is significantly longer than some other similar medications. This doesn’t mean you’ll have continuous physical responses for 36 hours—rather, you’ll have the ability to respond naturally to stimulation during this window. The effect gradually diminishes over time.

Q7: Will Megalis affect my fertility or harm my partner?

There is no evidence that Tadalafil affects male fertility or harms sexual partners. The medication is not transferred in amounts that would affect a partner. However, this medicine does not provide protection against sexually transmitted infections, so appropriate protective measures should still be used when necessary.

Medical Disclaimer

Important Legal and Medical Information:

The information provided on this page is intended for educational purposes only and should not replace professional medical advice, diagnosis, or treatment. CheapMedsKart.com provides this content to help patients better understand their medications, but it is not a substitute for consultation with a qualified healthcare provider.

Please note:

  • Always consult your doctor: Before starting, stopping, or changing any medication, including Megalis tablets, you must consult with a licensed healthcare professional who knows your complete medical history.
  • Individual results vary: The information presented represents general guidelines and typical responses. Your experience may differ based on your unique health situation, age, other medications, and underlying conditions.
  • Prescription required: Megalis is a prescription-only medication. Purchase and use of this medicine without a valid prescription from a licensed healthcare provider is illegal and potentially dangerous to your health.
  • Not for self-diagnosis: Never use this information to diagnose yourself or others. Only qualified medical professionals can provide accurate diagnoses and appropriate treatment plans.
  • Medical emergencies: If you experience serious side effects or medical emergencies, seek immediate medical attention by calling emergency services or visiting the nearest emergency room.
  • Accuracy disclaimer: Although we strive to provide accurate and up-to-date information, medical knowledge is constantly evolving. Always verify information with your healthcare provider and refer to the official patient information leaflet included with your medication.
  • No guarantees: CheapMedsKart.com makes no guarantees regarding treatment outcomes, effectiveness, or safety for any individual user. Responses to medication vary significantly among individuals.
  • Liability: Use of information from this website is at your own risk. CheapMedsKart.com, its owners, employees, and affiliates are not liable for any adverse outcomes resulting from use of this information or medications purchased through our platform.

For Your Safety: Always purchase medications from licensed, verified pharmacies. Verify that your online pharmacy requires a valid prescription and operates under proper regulatory oversight. Counterfeit medications pose serious health risks.

Questions or Concerns? Contact your healthcare provider, pharmacist, or our licensed pharmacy team for personalized guidance regarding your medication.


Medical information changes regularly. Always consult current medical resources and your healthcare provider for the most up-to-date guidance.

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300 Tablet, 90 Tablet, 120 Tablet, 150 Tablet

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Price range: $90.00 through $315.00

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